The RADIL has a primary research mission of investigating diseases in research animals. Significant outcomes of these disease studies include identification and characterization of newly-recognized disease agents, description of animal models of human disease and development of state-of-the-art diagnostic tests to identify rodent disease agents that would adversely affect animal-based research. The combined activiities of the RADIL research and diagnostic laboratories naturally provide an enriched environment for training of veterinary residents and graduate students.
11.19.2009
In the past, in order to accurately determine the presence of pinworms in an animal has required a post-mortem direct exam. With the introduction of RADIL's new PCR assay which tests for both Syphacia obvelata and Aspiculuris tetraptera, antemortem testing can now be performed with highly accurate results. RADIL's Pinworm PCR assay is nearly as sensitive as the direct exam and has the advantage that the animal does not need to be euthanized for evaluation. In studies, it was also more sensitive than either of the two antemortem tests (tape test and fecal float).
Pinworm by PCR evaluation will be available beginning December 1, 2009 as part of the Mouse Basic , Mouse Comprehensive and Rat Basic Fecal Panels, as a Helicobacter & Pinworm panel, or as a stand-alone assay. For more information and pricing, please click here.
( for more info click here )11.19.2009
At this year's National AALAS Meeting in Denver, Colorado, RADIL 
introduced a breakthrough serologic testing technology that will offer clients an increased level of results confidence for the most prevalent mouse and rat agents. MFI2 represents an advanced approach to serologic monitoring for laboratory animal pathogens, providing the highest level of diagnostic accuracy available. By evaluating multiple antigens for each agent, primary and confirmatory testing now occur at the same time, saving time and increasing the predictive value of the final results. Clients will begin seeing multiple antigens reported on case reports as of December 1, 2009.
For more information regarding MFI2, please visit the Serology section of this site.
( for more info click here )Mock OB, Casteel SW, Darmani NA, Shaddy JH, Besch-Williford C, Towns LC. 1,3-dinitrobenzene toxicity in the least shrew, Cryptotis parva. Environ Toxicol Chem. 2005 Oct;24(10):2519-25
Hsu C, Carter DB, Williams D, Besch-Williford C. Haematoloechus sp. infection in wild-caught northern leopard frogs (Rana pipiens). Contemp Top Lab Anim Sci. 2004 Nov;43(6):14-6; quiz 58.
St Claire MB, Kennett MJ, Besch-Williford CL. Vitamin A toxicity and vitamin E deficiency in a rabbit colony. Contemp Top Lab Anim Sci. 2004 Jul;43(4):26-30.
Carter DB, Kennett MJ, Franklin CL. Use of perphenazine to control cannibalism in DBA/1 mice. Comp Med. 2002 Oct;52(5):452-5. Erratum in: Comp Med. 2003 Apr;53(2):218.
Simmons JH, Purdy GA, Franklin CL, Trottier P, Churchill AE, Russell RJ, Besch-Williford CL, Riley LK. Characterization of a novel parainfluenza virus, caviid parainfluenza virus 3, from laboratory guinea pigs (Cavia porcellus). Comp Med. 2002 Dec;52(6):548-54.
Kendall LV, Riley LK, Hook RR Jr, Besch-Williford CL, Franklin CL. Characterization of lymphocyte subsets in the bronchiolar lymph nodes of BALB/c mice infected with cilia-associated respiratory bacillus. Comp Med. 2002 Aug;52(4):322-7.
Myles MH, Foltz CJ, Shinpock SG, Olszewski RE, Franklin CL. Infertility in CFW/R1 mice associated with cystic dilatation of the bulbourethral gland. Comp Med. 2002 Jun;52(3):273-6.
Ramos-Vara, JA, Franklin CL, Miller MA. Bronchitis and bronchiolitis in a cat with CAR bacillus-like organisms and intraepithelial globule leukocytes. Vet Pathol. 39:501-504, 2002
Mock OB, Casteel SW, Darmani NA, Shaddy JH, Besch-Williford C, Towns LC. Anatomic and physiologic reference values in least shrews (Cryptotis parva). Comp Med. 2001 Dec;51(6):534-7.
Criley JM, Carty AJ, Besch-Williford CL, Franklin CL. Coxiella burnetii infection in C.B-17 scid-bg mice xenotransplanted with fetal bovine tissue. Comp Med. 2001 Aug;51(4):357-60.
Simmons JH, Riley LK, Franklin CL, Besch-Williford CL. Hamster polyomavirus infection in a pet Syrian hamster (Mesocricetus auratus). Vet Pathol. 2001 Jul;38(4):441-6.
Kendall LV, Riley LK, Hook RR Jr, Besch-Williford CL, Franklin CL. Differential interleukin-10 and gamma interferon mRNA expression in lungs of cilium-associated respiratory bacillus-infected mice. Infect Immun. 2001 Jun;69(6):3697-702.
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