In the past, in order to accurately determine the presence of pinworms in an animal has required a post-mortem direct exam.  With the introduction of RADIL's new PCR assay which tests for both Syphacia obvelata and Aspiculuris tetraptera, antemortem testing can now be performed with highly accurate results.  RADIL's Pinworm PCR assay is nearly as sensitive as the direct exam and has the advantage that the animal does not need to be euthanized for evaluation.  In studies, it was also more sensitive than either of the two antemortem tests (tape test and fecal float).

Pinworm by PCR evaluation will be available beginning December 1, 2009 as part of the Mouse Basic , Mouse Comprehensive and Rat Basic Fecal Panels, as a Helicobacter & Pinworm panel, or as a stand-alone assay.  For more information and pricing, please click here. 

At this year's National AALAS Meeting in Denver, Colorado, RADIL introduced a breakthrough serologic testing technology that will offer clients an increased level of results confidence for the most prevalent mouse and rat agents.  MFI² represents an advanced approach to serologic monitoring for laboratory animal pathogens, providing the highest level of diagnostic accuracy available.   By evaluating multiple antigens for each agent, primary and confirmatory testing now occur at the same time, saving time and increasing the predictive value of the final results.  Clients will begin seeing multiple antigens reported on case reports as of December 1, 2009.

For more information regarding MFI², please visit the Serology section of this site.

Are your cell lines contaminated

or misidentified?

THE PROBLEM.......

• 15-30% of all cell lines are cross contaminated with other cell lines or are misidentified (Science, Feb. 2007).
• Contamination results in invalid data PLUS wasted time and money.
• Journals are considering requiring authentication of cell lines prior to publication .
• NIH recently issued a notice discussing the need for cell authentication for studies proposed in grant applications.

THE SOLUTION.......

Authenticate human and rodent cell lines

• Verifies the identity of a cell line by generating a genetic profile.
• Human cell lines are autheniticated using 9 short tandem repeat (STR) loci.
• Mouse and rat lines are authenticated using a panel of microsatellite markers.
• This analysis can be used to verify the identity of a cell line or establish the genetic profile of a unique cell line.
   

Detect cross-contamination of cell cultures with other cell lines

• Can detect presence of DNA of human, mouse, rat, African green monkey or Chinese hamster origin using a multiplex PCR assay.
• Detects as little as 1-5% inter-species cross contamination.
• Species-specific assays are also available for rabbit, pig and dog.

Check for Mycoplasma or other pathogens

• Customize the analysis of your cell line by adding additional testing for Mycoplasma sp., human pathogens (h-IMPACT) or rodent pathogens (IMPACT).

When to test?

• When a new cell line is established or acquired.
• As a standard quality control measure when beginning a new series of experiments.
• When cell line performance is inconsistent or results are unexpected.
• To establish a genetic profile for a new or unique mouse, rat or human cell line.

Additional Tests......

Cell Check (mouse or rat)............... $150.00

Cell Check (human)........................... 125.00

Add Mycoplasma..............................   49.50

Add Parvo.........................................   71.60

Add Mycoplasma and Parvo............. 121.10

Add h-IMPACT................................... 215.45

Inter- or Intra-species Contamination.  85.00